Discoveries
Expert guides on genetic-testing coverage, coding, and utilization management — for molecular labs, medical directors, genetic counselors, ordering clinicians, and revenue-integrity teams. Every guide is anchored to primary sources: CMS coverage policy, ICD-10-CM, CPIC, and ClinGen/GenCC.
MolDX MASLD/MASH Biomarker Coverage: 2026 LCD Guide
Four MolDX MACs put identical MASLD/MASH biomarker LCDs into effect on August 10, 2026. Here are the sequential coverage gates, the two-group ICD-10 requirement, and the Z-Code and frequency rules labs must configure now.
National MolDX Expansion: What Labs Need to Know
CMS floated nationwide MolDX registration in its CRUSH RFI. The claims data behind it, how the industry responded, and what labs should do now.
Why Genetic Testing Claims Get Denied — and How Labs Prevent Them
Denial rates for advanced genetic testing have climbed past 27%. The six predictable reasons claims fail — and the upstream checks that prevent them.
ICD-10 Codes for Genetic Testing: The Complete Coding Guide
The code families that establish medical necessity — Z15.0x, Z80.x, Z85.x, Z14.x — and the vague codes that quietly cause denials.
Medicare Coverage for Genetic Testing: LCD, NCD & MolDX
How Medicare decides what gets paid: NCD 90.2, MAC-level LCDs, the MolDX program, and the DEX Z-Code registry — plus a step-by-step coverage check.
Genetic Testing & Coverage Glossary
Plain-English definitions of the terms that decide whether a test is ordered correctly and paid for — CPIC, ClinGen, LCD vs. NCD, MolDX, Z-Codes, VUS.
New guides are added regularly. For the platform these guides support, see ScreenMyGene: genetic-test decision support or explore pharmacogenomics, hereditary cancer, neurology, and metabolic disease.